Ramón Ayala started playing the accordion in 1951. He learned to play the drums in 1954. In 1955, he picked up the bajo sexto after his father Pedro Ayala, El Monarca del Acordeón, showed him his first two chords. By 1956, Ramón Ayala and his brother Pedro Ayala Jr., who played the accordion, joined their father in Pedro Ayala y Su Conjunto. Since 1956, Ramón Ayala has gone on to record for over a dozen studios releasing 88 recordings in album, single, cassette and CD formats. Ramón Ayala has recorded with Freddy Fender, Paulino Bernal and Esteban Jordan, among others. To date, he has released 105 recordings.